Increased Vaspin Levels Are Associated with Beneficial Metabolic Outcome Pre- and Post-Bariatric Surgery
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Increased Vaspin Levels Are Associated with Beneficial Metabolic Outcome Pre- and Post-Bariatric Surgery
PURPOSE Vaspin (visceral-adipose-tissue-derived-serine-protease-inhibitor) is a recently identified adipokine with putative insulin-sensitizing properties. Plasma vaspin responses to surgery-induced weight loss are sparse and contradictory. DESIGN AND PARTICIPANTS We evaluated changes in vaspin levels and relationship to post-operative outcomes in men (n = 22) and women (n = 55) undergoing bi...
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BACKGROUND An increase of plasma kynurenine concentrations, potentially bioactive metabolites of tryptophan, was found in subjects with obesity, resulting from low-grade inflammation of the white adipose tissue. Bariatric surgery decreases low-grade inflammation associated with obesity and improves glucose control. OBJECTIVE Our goal was to determine the concentrations of all kynurenine metab...
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متن کاملMetabolic consequences of bariatric surgery.
Obesity has gained prominence as a main cause of preventable illness and death in the developed world. Surgical therapy for obesity is extremely effective in terms of weight reduction and amelioration of comorbidities. Bariatric procedures are not simply cosmetic operations, however, and involve considerable manipulation of the gastrointestinal tract to induce weight loss. The metabolic consequ...
متن کاملMetabolic Effects of Bariatric Surgery
Obesity and its associated comorbidities are an ongoing health care problem worldwide [1]. It is well known that obese patients are at increased risk for the development of diabetes, hypertension, hyperlipidemia, sleep apnea, osteoarthritis, and other degenerative diseases [2]. Bariatric surgery has demonstrated to achieve, on top of significant weight reduction, also long-term control of metab...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0111002